Related Experiment Video
Updated: Jun 28, 2026

Use of Hematopoietic Stem Cell Transplantation to Assess the Origin of Myelodysplastic Syndrome
Published on: October 3, 2018
Myelodysplastic syndromes: more prevalent than we know
Satinderpal K Sandhu1, Mikkael A Sekeres
1Case Western Reserve University School of Medicine, and Senior Health and Wellness Center, MetroHealth Medical Center, Cleveland, Ohio, USA.
Abstract:
Myelodysplastic syndromes (MDS), a hematopoietic disorder for which formal tracking began as recently as 2001, is rapidly gaining recognition as a cause of anemia. The incidence of MDS increases with age and is considered the most common hematologic cancer in the elderly. The disease can follow an indolent course or rapidly progress to acute myelogenous leukemia (AML). Comorbidities and functional issues make this disease challenging to diagnose and treat in geriatric patients. This article reviews the epidemiology, classification, and treatment options for MDS.
Related Concept Videos
Alternative RNA Splicing
There are five types of alternative RNA splicing that vary in the ways the pre-mRNA segments are removed or retained in the mature mRNA. The first...
Differentiation of Common Myeloid Progenitor Cells
Multiple Sclerosis l: Introduction
Cellular Adaptation IV: Dysplasia and Metaplasia
Disorders of Erythrocytes
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
Prevalence and Incidence
Prevalence indicates the proportion of individuals in a population who have a specific disease or health condition at a...

