Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genome Annotation and Assembly03:36

Genome Annotation and Assembly

The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
Anatomical Terminology01:20

Anatomical Terminology

Knowledge of anatomy is essential to understand human biology and medicine. Anatomists and health care professionals use standard terminology to describe the human body with more precision and no ambiguity. Anatomical terms have mostly Greek and Latin-derived roots. Because these languages are rarely used in conversation, the meaning of words remains the same. Each term is made up of a root in between the prefixes and suffixes. The root of a term often refers to an organ, tissue, or condition,...
Schemas01:42

Schemas

A schema is a mental construct consisting of a cluster or collection of related concepts (Bartlett, 1932). There are many different types of schemata, and they all have one thing in common: schemata are a method of organizing information that allows the brain to work more efficiently. When a schema is activated, the brain makes immediate assumptions about the person or object being observed.
Ligand Binding Sites02:40

Ligand Binding Sites

Proteins are dynamic macromolecules that carry out a wide variety of essential processes; however, the activities of most proteins depend on their interactions with other molecules or ions, known as ligands.
Protein-ligand interactions are quite specific; even though numerous potential ligands surround a cellular protein at any given time, only a particular ligand can bind to that protein. Moreover, a ligand binds only to a dedicated area on the surface of the protein, known as the...
Ligand Binding Sites02:40

Ligand Binding Sites

Proteins are dynamic macromolecules that carry out a wide variety of essential processes; however, the activities of most proteins depend on their interactions with other molecules or ions, known as ligands.
Protein-ligand interactions are quite specific; even though numerous potential ligands surround a cellular protein at any given time, only a particular ligand can bind to that protein. Moreover, a ligand binds only to a dedicated area on the surface of the protein, known as the...
ER Retrieval Pathway01:45

ER Retrieval Pathway

In the secretory pathway, vesicles transport proteins from one cellular compartment to another in forward transport to deliver the protein to its correct location. Occasionally, misfolded proteins and incorrect proteins escape their original compartments, and a retrieval pathway is used to return the escaped proteins to their original compartment.
The ER uses many checkpoints to prevent the entry of incorrectly folded or a resident protein as cargo onto a transport vesicle. These mechanisms...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Graphic Descriptor Ontology: An ontology for semantic annotation of graphics and its application to graphic libraries of anatomical standards.

PloS one·2026
Same author

Extraction of distant recurrence sites for breast cancer patients from free-text clinical notes using large language models.

Journal of biomedical informatics·2026
Same author

Creation of Radiology Teaching Content with STELLA-A STandardized Electronic Learning Library and Application Platform.

Academic radiology·2025
Same author

Out-of-the-Box Large Language Models for Detecting and Classifying Critical Findings in Radiology Reports Using Various Prompt Strategies.

AJR. American journal of roentgenology·2025
Same author

Open-Source Hybrid Large Language Model Integrated System for Extraction of Breast Cancer Treatment Pathway From Free-Text Clinical Notes.

JCO clinical cancer informatics·2025
Same author

Developing libraries of semantically-augmented graphics as visual standards for biomedical information systems.

Journal of biomedical informatics·2025

Related Experiment Video

Updated: Jun 28, 2026

A Web Tool for Generating High Quality Machine-readable Biological Pathways
08:01

A Web Tool for Generating High Quality Machine-readable Biological Pathways

Published on: February 8, 2017

Web service access to semantic web ontologies for data annotation.

Joshua D Franklin1, José L V Mejino, Landon T Detwiler

  • 1Structural Informatics Group, Dept. of Biological Structure, Univ. of Washington, Seattle, WA, USA.

AMIA ... Annual Symposium Proceedings. AMIA Symposium
|November 13, 2008
PubMed
Summary
This summary is machine-generated.

Semantic web technologies offer new methods for applying ontology support in biomedical applications. This enables more efficient data annotation and integration for researchers.

More Related Videos

Applying Cheminformatics to Develop a Structure Searchable Database of Analytical Methods
05:34

Applying Cheminformatics to Develop a Structure Searchable Database of Analytical Methods

Published on: June 6, 2025

Related Experiment Videos

Last Updated: Jun 28, 2026

A Web Tool for Generating High Quality Machine-readable Biological Pathways
08:01

A Web Tool for Generating High Quality Machine-readable Biological Pathways

Published on: February 8, 2017

Applying Cheminformatics to Develop a Structure Searchable Database of Analytical Methods
05:34

Applying Cheminformatics to Develop a Structure Searchable Database of Analytical Methods

Published on: June 6, 2025

Area of Science:

  • Biomedical Informatics
  • Semantic Web Technologies

Background:

  • Biomedical applications require robust data management for annotation and integration.
  • Traditional methods face challenges in adaptability and efficiency.

Purpose of the Study:

  • To explore the application of semantic web technologies for ontology support in biomedical informatics.
  • To demonstrate efficient and adaptable deployment methodologies.

Main Methods:

  • Leveraging recent advances in semantic web technologies.
  • Developing and deploying ontology support systems.
  • Focusing on adaptable methodologies for biomedical applications.

Main Results:

  • Semantic web technologies provide a viable methodology for ontology support.
  • Efficient and adaptable deployment is achievable.
  • Enhanced data annotation and integration capabilities.

Conclusions:

  • Semantic web technologies are crucial for advancing biomedical data management.
  • Ontology support deployment is optimized through these technologies.
  • Future biomedical applications can benefit from this methodology.