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Related Concept Videos

Drug Classes and Categories01:25

Drug Classes and Categories

Drugs can be classified according to their chemical composition or their intended therapeutic application. For instance, anti-infective agents that possess the ability to eliminate pathogens or suppress their growth and reproduction can be grouped based on the organisms they target or their chemical structure. Furthermore, drugs can be divided into prescription, nonprescription, or controlled substances. Prescription medications, such as antibiotics, require oversight from a licensed healthcare...
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During the development of a new pharmaceutical, the manufacturer initially assigns a code name to the drug. Once approved, the drug receives a United States Adopted Name (USAN)—a generic, nonproprietary designation. Upon being listed in the United States Pharmacopeia, this nonproprietary name becomes the drug's official name. Additionally, the manufacturer assigns a proprietary name or trademark, which serves as the brand name under which the drug is marketed. It is worth noting that the same...
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Modified-release drug delivery systems improve drug efficacy and minimize side effects by controlling the rate and location of drug release. These systems fall into three categories: rate-programmed, stimuli-activated, and site-targeted.Rate-programmed systems release drugs at a predetermined rate, maintaining consistent therapeutic levels and reducing fluctuations that could lead to toxicity or subtherapeutic effects. These systems use polymeric matrices, reservoir-based designs, or osmotic...
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Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood at designated intervals to ensure the drug concentration stays within a therapeutic range. This monitoring is crucial for optimizing individual dosage regimens, enhancing therapeutic efficacy, and minimizing drug-related toxicity. TDM is vital for drugs with narrow therapeutic windows, significant variability in pharmacokinetics, and a clear correlation between plasma levels and...
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Cardiovascular diseases, encompassing a range of conditions, can significantly affect the heart's operations and the overall circulatory system. These conditions impair the heart's ability to pump blood, leading to a deficit in oxygen supply to crucial organs. Anomalies in the heart's electrical system, known as arrhythmias, can cause heartbeats to accelerate or slow down. Usually, heart rates increase during physical activity and decrease while resting or sleeping. However, frequent irregular...
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Updated: Jun 28, 2026

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
10:17

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

Published on: April 23, 2019

Comparing drug classification systems.

Anne Mahoney1, Jonathan Evans

  • 1Siemens Healthcare, Malvern, PA, USA.

AMIA ... Annual Symposium Proceedings. AMIA Symposium
|November 13, 2008
PubMed
Summary
This summary is machine-generated.

Drug classification systems should be consistent, but we found discrepancies in how multiple-indication drugs are categorized across four major schemas. This highlights a need for improved standardization in pharmaceutical categorization.

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Applying Cheminformatics to Develop a Structure Searchable Database of Analytical Methods
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High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
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Published on: April 23, 2019

Applying Cheminformatics to Develop a Structure Searchable Database of Analytical Methods
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Published on: June 6, 2025

Area of Science:

  • Pharmacology
  • Drug Classification
  • Medical Informatics

Background:

  • Drug classification systems are crucial for organizing medications by mechanism of action, physiological effects, and therapeutic indications.
  • No single system perfectly meets all classification needs, but consistency among systems using similar principles is expected.
  • Existing schemas aim to provide structured hierarchies for drug information.

Purpose of the Study:

  • To evaluate the consistency of drug classification across widely used schemas.
  • To identify discrepancies in the categorization of drugs with multiple therapeutic indications.
  • To assess the need for standardization in drug classification methodologies.

Main Methods:

  • Analysis of four prominent drug classification systems.
  • Comparative review of drug categorization for medications with multiple therapeutic uses.
  • Identification and documentation of inconsistencies across the selected schemas.

Main Results:

  • Significant discrepancies were found in how drugs with multiple therapeutic indications are classified.
  • The four analyzed schemas exhibit variability in assigning drugs to hierarchical categories.
  • Inconsistencies were observed in the application of underlying classification principles.

Conclusions:

  • Current drug classification systems lack uniformity, particularly for drugs with diverse therapeutic applications.
  • The observed discrepancies may impact drug information retrieval, clinical decision-making, and pharmacovigilance.
  • There is a clear need for enhanced consistency and standardization in drug classification schemas.