Developing a distributed research network to conduct population-based studies and safety surveillance
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Updated: Jun 28, 2026

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data
Published on: July 27, 2018
John H Holmes1, Jeffrey Brown, Sean Hennessy
1University of Pennsylvania School of Medicine, Philadelphia, PA, USA.
Abstract:
The Developing Evidence to Inform Decisions about Effectiveness (DEcIDE) centers at the HMO Research Network Center for Education and Research on Therapeutics (HMORN CERT) and the University of Pennsylvania are developing a design for a scalable distributed research network (DRN) to support a wide array of purposes related to therapeutics, including comparative effectiveness, safety, and utilization, as well as quality of care research. The project will implement a system prototype, conduct a proof of principle research project on hypertension therapy, and make recommendations for future expansion of the network.
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