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Related Concept Videos

Development of the Oral Microbiota01:28

Development of the Oral Microbiota

The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
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Regression Toward the Mean

Regression toward the mean (“RTM”) is a phenomenon in which extremely high or low values—for example, and individual’s blood pressure at a particular moment—appear closer to a group’s average upon remeasuring. Although this statistical peculiarity is the result of random error and chance, it has been problematic across various medical, scientific, financial and psychological applications. In particular, RTM, if not taken into account, can interfere when researchers try to extrapolate results...

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Related Experiment Video

Updated: Jun 28, 2026

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
14:43

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

Current research in preterm birth.

Dhelia M Williamson1, Karon Abe, Christopher Bean

  • 1Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA. djw8@cdc.gov

Journal of Women'S Health (2002)
|November 13, 2008
PubMed
Summary
This summary is machine-generated.

Preterm birth is a major cause of infant death and disability in the US. The Centers for Disease Control and Prevention (CDC) is researching its causes and risk factors to improve maternal and infant health outcomes.

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Area of Science:

  • Public Health
  • Reproductive Health
  • Neonatal Health

Background:

  • Preterm birth is a primary driver of infant mortality and morbidity in the United States.
  • It is responsible for over 70% of neonatal deaths and nearly half of long-term neurological disabilities in infants.
  • Understanding the multifaceted causes of preterm birth is critical for public health initiatives.

Purpose of the Study:

  • To investigate the complex factors contributing to preterm birth.
  • To identify high-risk pregnancies through genetic and biological markers.
  • To develop community-based strategies for reducing preterm birth rates.

Main Methods:

  • Collaborative research involving state health departments, universities, communities, and healthcare providers.
  • Exploration of genetic, biological, clinical, behavioral, social, and community determinants of preterm birth.
  • Investigating the interplay between psychosocial stress, immune responses, and preterm birth risk.

Main Results:

  • Ongoing research aims to identify early detection markers for high-risk pregnancies.
  • Studies are enhancing the understanding of the links between stress, inflammation, and preterm birth.
  • Community strategies are being designed to improve pregnant women's health and reduce preterm birth.

Conclusions:

  • The Centers for Disease Control and Prevention (CDC) is actively engaged in public health research to understand and address preterm birth.
  • Elucidating the complex interactions of various determinants is key to mitigating preterm birth.
  • Continued research will inform interventions to decrease infant mortality and morbidity associated with preterm birth.