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A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
Published on: January 12, 2018
Current research in preterm birth
Dhelia M Williamson1, Karon Abe, Christopher Bean
1Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA. djw8@cdc.gov
Insights
Preterm birth is a major cause of infant death and disability in the US. The Centers for Disease Control and Prevention (CDC) is researching its causes and risk factors to improve maternal and infant health outcomes.
Area of Science:
- Public Health
- Reproductive Health
- Neonatal Health
Background:
- Preterm birth is a primary driver of infant mortality and morbidity in the United States.
- It is responsible for over 70% of neonatal deaths and nearly half of long-term neurological disabilities in infants.
- Understanding the multifaceted causes of preterm birth is critical for public health initiatives.
Purpose of the Study:
- To investigate the complex factors contributing to preterm birth.
- To identify high-risk pregnancies through genetic and biological markers.
- To develop community-based strategies for reducing preterm birth rates.
Main Methods:
- Collaborative research involving state health departments, universities, communities, and healthcare providers.
- Exploration of genetic, biological, clinical, behavioral, social, and community determinants of preterm birth.
- Investigating the interplay between psychosocial stress, immune responses, and preterm birth risk.
Main Results:
- Ongoing research aims to identify early detection markers for high-risk pregnancies.
- Studies are enhancing the understanding of the links between stress, inflammation, and preterm birth.
- Community strategies are being designed to improve pregnant women's health and reduce preterm birth.
Conclusions:
- The Centers for Disease Control and Prevention (CDC) is actively engaged in public health research to understand and address preterm birth.
- Elucidating the complex interactions of various determinants is key to mitigating preterm birth.
- Continued research will inform interventions to decrease infant mortality and morbidity associated with preterm birth.
Abstract:
Preterm birth is one of the leading causes of infant mortality and the leading cause of infant morbidity in the United States. It accounts for >70% of neonatal deaths and almost half of long-term neurological disabilities. The Centers for Disease Control and Prevention (CDC) is collaborating with state health departments, universities, communities, and healthcare providers to understand why preterm births occur and how to address preterm birth risk factors. These collaborations include identification of genetic and other biological markers for the early detection of women at high risk of preterm birth; improving understanding of the relationships among psychosocial stress, immune and inflammatory responses, and preterm risk; and designing community strategies to improve the health of pregnant women. By conducting public health research activities that explore the genetic, biological, clinical, behavioral, social, and community determinants of preterm birth, CDC will continue to elucidate the complex interactions of these factors and how they influence preterm birth.
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