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Modeling and Simulations of Olfactory Drug Delivery with Passive and Active Controls of Nasally Inhaled Pharmaceutical Aerosols

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Relationship between nasal cavity volume changes and nasalance.

H Birkent¹, U Erol, M Ciyiltepe

¹Department of Otolaryngology-Head and Neck Surgery, Gulhane Military Medical Academy, Ankara, Turkey. hbirkent@yahoo.com

The Journal of Laryngology and Otology

|November 13, 2008

Summary

This summary is machine-generated.

Nasal decongestants increase nasal cavity volume and nasalance scores. However, changes in nasalance may not solely depend on nasal cavity volume, suggesting other contributing factors.

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Published on: April 8, 2013

Area of Science:

Otolaryngology
Speech Science
Acoustic Physiology

Background:

Nasal cavity patency and volume influence voice acoustics.
Understanding these relationships is crucial for voice production research.

Purpose of the Study:

To investigate the impact of nasal decongestants on nasal volumes and nasalance.
To explore the correlation between nasal volume changes and nasalance scores.

Main Methods:

Acoustic rhinometry and nasometry were employed in 21 adult volunteers.
Measurements were taken before and after nasal decongestant administration.

Main Results:

Nasal decongestants significantly increased nasalance scores and all measured acoustic rhinometric parameters (e.g., cross-sectional areas, volumes).
No significant correlation was found between alterations in nasalance scores and acoustic rhinometric parameters.

Conclusions:

Nasal decongestion demonstrably increases both nasalance scores and nasal cavity volumes.
The study suggests that factors beyond nasal cavity volume changes influence nasalance scores.