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Updated: Jun 28, 2026

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
Published on: January 15, 2022
Various types of plaque disruption in culprit coronary artery visualized by optical coherence tomography in a patient
Takashi Tanimoto1, Toshio Imanishi, Atsushi Tanaka
1Department of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan. taka-t@wakayama-med.ac.jp
Abstract:
A 58-year-old man underwent cardiac catheterization for unstable angina. The coronary angiogram revealed severe stenosis of the right coronary artery. Although 20-MHz, phased-array intravascular ultrasound (IVUS) only visualized eccentric, low echoic plaque at the culprit site, optical coherence tomography (OCT) clearly revealed ruptured plaque and an intraluminal thrombus. OCT also revealed a small ruptured plaque and an eroded plaque with intraluminal thrombi in a distal site remote from the culprit lesion, neither of which was visualized by IVUS.
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