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Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
07:36

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Published on: May 1, 2015

Lemierre's syndrome.

D N O'Dwyer1, S Ryan, T O'Keefe

  • 1St Vincent's University Hospital, Elm Park, Dublin 4, Ireland. daviodwyer@gmail.com

Irish Journal of Medical Science
|November 13, 2008
PubMed
Summary
This summary is machine-generated.

Lemierre's syndrome, a rare oropharyngeal infection, can cause internal jugular vein thrombosis. This case highlights diagnostic challenges in patients with pre-existing valvular heart disease.

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Last Updated: Jun 28, 2026

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
07:36

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Published on: May 1, 2015

Area of Science:

  • Otolaryngology
  • Infectious Diseases
  • Cardiology

Background:

  • Lemierre's syndrome is a rare but serious condition originating from oropharyngeal infections.
  • Fusobacterium necrophorum is the primary bacterial agent responsible for this syndrome.
  • Internal jugular vein thrombosis and metastatic infections are characteristic complications.

Observation:

  • A case study of a young female patient is presented.
  • The patient's history of valvular heart disease complicated the diagnosis.
  • Cardiac valve infections can mimic symptoms of Lemierre's syndrome.

Findings:

  • The study details the diagnostic process for a complex case of Lemierre's syndrome.
  • Investigation methods for identifying the infection and its complications are outlined.
  • Optimal management strategies for this rare disorder are discussed.

Implications:

  • Highlights the importance of considering Lemierre's syndrome in oropharyngeal infections, even with confounding factors.
  • Emphasizes the need for thorough investigation to differentiate from cardiac conditions.
  • Informs clinical practice regarding the diagnosis and management of this rare disease.