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Updated: Jun 28, 2026

Evaluation of Vascular Control Mechanisms Utilizing Video Microscopy of Isolated Resistance Arteries of Rats
Published on: December 5, 2017
Therapeutic control of the circulation
William Geoffrey Parkin1, Mark Stephen Leaning
1Applied Physiology Pty Ltd, Sydney, Australia. geoffrey.parkin@applied-physiology.com
Abstract:
By regarding the circulation from the perspective of the venous return, continuous therapeutic control of the mean arterial blood pressure, cardiac output and tissue oxygen flow can be seen to be the consequence of a series of equations based on conventionally measured variables. This approach permits a graphical solution to circulation guidance, open or closed loop control and goal directed therapy of broad general applicability.
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