Related Experiment Video
Updated: Jun 28, 2026

Techniques of Sleeve Gastrectomy and Modified Roux-en-Y Gastric Bypass in Mice
Published on: March 20, 2017
Obesity surgery results depending on technique performed: long-term outcome
J A Gracia1, M Martínez, M Elia
1Department of Surgery, Hospital Clínico Universitario Lozano Blesa, 50009, Zaragoza, Spain. josegraciasolanas@hotmail.com
Bariatric surgery outcomes vary long-term; biliopancreatic diversion (BPD) maintains weight loss, while vertical banded gastroplasty (VBG) and laparoscopic Roux-en-Y gastric bypass (LRYGBP) show weight regain. BPD offers sustained efficacy despite higher morbidity.
Area of Science:
- Bariatric Surgery
- Obesity Treatment
- Surgical Outcomes
Background:
- Long-term efficacy of bariatric surgery techniques requires analysis beyond 2 years.
- Weight regain and late complications are concerns with some procedures.
- Evaluating weight loss, morbidity, and mortality over 5 years is crucial.
Purpose of the Study:
- To analyze the long-term (5+ years) weight loss, morbidity, and mortality of bariatric surgical procedures.
- Compare the long-term effectiveness of vertical banded gastroplasty (VBG), biliopancreatic diversion (BPD), and laparoscopic Roux-en-Y gastric bypass (LRYGBP).
Main Methods:
- Retrospective cohort study of morbidly obese patients.
- Analysis of weight loss, morbidity, and mortality using the Bariatric Analysis And Reporting Outcome System (BAROS).
- Procedures included open VBG, open Scopinaro BPD, open modified BPD, and LRYGBP.
Main Results:
- Biliopancreatic diversion (BPD) groups maintained excellent weight results long-term, unlike VBG and LRYGBP which showed weight regain.
- Mortality rates: VBG 1.6%, BPD 1.2%, LRYGBP 0%.
- Late morbidities included protein malnutrition (up to 11% in Scopinaro BPD) and iron deficiency (up to 62% in Scopinaro BPD). Revision surgeries were required for VBG (14.5%), Scopinaro BPD (3.2%), and LRYGBP (0.8%).
Conclusions:
- More complex bariatric procedures (BPD) increase effectiveness but also morbidity/mortality.
- Laparoscopic Roux-en-Y gastric bypass (LRYGBP) is safe and effective for morbid obesity.
- Modified BPD (75-225 cm) is suitable for superobesity; VBG requires careful patient selection due to high long-term failure rates.
Related Concept Videos
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...

