Related Experiment Video
Updated: Jun 28, 2026

Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat
Published on: November 18, 2018
Levosimendan and severe pulmonary hypertension during open heart surgery
Ferit Cicekcioglu1, Ali Ihsan Parlar, Ozgur Ersoy
1Kalp ve Damar Cerrahisi Klinigi (Cardiovascular Surgery Clinic), Turkiye Yuksek Ihtisas Hastanesi, Sihhiye, Ankara 06100, Turkey.
Abstract:
Weaning from cardiopulmonary bypass is the most important stage during mitral valve surgery, especially in patients with severe pulmonary hypertension. We report two patients with severe pulmonary hypertension who were operated on because of valvular heart disease. To reduce the pulmonary artery pressure, levosimendan was used because of its vasodilatory and cytoprotective effects. All patients tolerated the operation and levosimendan administration. Their postoperative course was uneventful. Levosimendan can be used to treat pulmonary hypertension during operations for heart valve disease. Patients clearly benefit from the vasodilator action of the drug for reducing pulmonary artery pressure.
Related Concept Videos
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Heart Failure Drugs: Inotropic Agents
Mitral Stenosis III: Medical Management
Heart Failure V: Medical Management
Heart Failure Drugs: β-Blockers
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
