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Eukaryotic initiation factor 5A: the molecular form of the hypusine-containing protein from human erythrocytes
S I Chung1, M H Park, J E Folk
1National Institute of Dental Research, National Institutes of Health, Bethesda, MD 20892.
Biochimica Et Biophysica Acta
|February 15, 1991
Abstract:
Eukaryotic initiation factor 5A (eIF-5A, formerly known as eIF-4D) purified from human erythrocytes has been found to have a monomeric molecular weight between 17,500 and 18,000. In this study, using exclusion chromatography and analytical ultracentrifugation, we demonstrate that eIF-5A normally exists as a dimer in solution and appears to be capable of undergoing reversible association to form higher polymers.