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Updated: Jun 28, 2026

Assessment of Vascular Function in Patients With Chronic Kidney Disease
08:50

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

Endothelial dysfunction in African-Americans.

Pawan D Patel1, Jose L Velazquez, Rohit R Arora

  • 1Department of Medicine, The Chicago Medical School, Chicago, IL 60064, United States.

International Journal of Cardiology
|November 14, 2008
PubMed
Summary
This summary is machine-generated.

Vascular endothelial dysfunction is a key factor in the high rates of cardiovascular disease among African Americans. Early detection and intervention in individuals, even those who appear healthy, may prevent future cardiac events.

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Last Updated: Jun 28, 2026

Assessment of Vascular Function in Patients With Chronic Kidney Disease
08:50

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

Area of Science:

  • Cardiovascular Science
  • Public Health

Background:

  • Atherosclerosis, a leading cause of death, starts with endothelial dysfunction.
  • African Americans experience disproportionately high rates of cardiovascular disease (CVD) morbidity and mortality.

Purpose of the Study:

  • To review the role of vascular endothelial dysfunction in the excess CVD burden among African Americans.
  • To highlight the potential of early detection of endothelial dysfunction for preventing adverse cardiovascular outcomes.

Main Methods:

  • Literature review focusing on endothelial dysfunction and cardiovascular disease in African Americans.

Main Results:

  • Endothelial dysfunction is a critical determinant of future atherosclerotic outcomes.
  • This dysfunction contributes significantly to the elevated CVD burden in the African American population.

Conclusions:

  • Vascular endothelial dysfunction serves as a crucial indicator for future atherosclerotic events in African Americans.
  • Early detection and therapeutic interventions in at-risk individuals, including those appearing healthy, are vital for preventing subsequent cardiac events and reducing mortality.