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The diagnosis and management of globus: a perspective from Japan

Nobuhiko Oridate1, Noriko Nishizawa, Satoshi Fukuda

  • 1Department of Otolaryngology - Head and Neck Surgery, Hokkaido University Graduate School of Medicine, Japan. noridate@med.hokudai.ac.jp

Current Opinion in Otolaryngology & Head and Neck Surgery
|November 14, 2008
PubMed

Insights

Globus symptoms are linked to gastroesophageal reflux disease (GERD). A practical approach divides patients into GERD/laryngopharyngeal reflux (LPR)-induced or non-GERD/LPR groups for targeted management.

Area of Science:

  • Gastroenterology
  • Otolaryngology

Background:

  • Globus pharyngeus is a common condition with multifactorial etiology.
  • Management strategies for globus remain a subject of debate.
  • Recent advancements in understanding globus etiology and diagnosis are emerging.

Purpose of the Study:

  • To discuss recent findings in the etiology and diagnosis of globus.
  • To present a subjective opinion on the management of globus.
  • To introduce a practical approach for classifying globus patients.

Main Methods:

  • Review of current literature on globus etiology and diagnosis.
  • Analysis of the association between globus symptoms and gastroesophageal reflux disease (GERD).
  • Discussion of diagnostic limitations and empirical management strategies.

Main Results:

  • A significant association exists between GERD and higher globus symptom scores.
  • Patients with globus can be practically divided into GERD/laryngopharyngeal reflux (LPR)-induced and non-GERD/LPR groups.
  • Empirical treatment targeting GERD is considered justified in globus management due to diagnostic challenges.

Conclusions:

  • A practical framework is proposed for categorizing patients with globus.
  • This classification aids in tailoring management strategies based on the presence of GERD/LPR.
  • Further research may improve diagnostic discrimination between patient subgroups.
Abstract

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