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Respiratory Syncytial Virus Disease

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Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...

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Common Respiratory Disorders

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Related Experiment Video

Updated: Jun 28, 2026

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma

Published on: March 11, 2014

Recurrent respiratory papillomatosis: update 2008.

Thomas Q Gallagher¹, Craig S Derkay

¹Department of Otolaryngology - Head and Neck Surgery, Naval Medical Center, Portsmouth, USA.

Current Opinion in Otolaryngology & Head and Neck Surgery

|November 14, 2008

Summary

Recurrent respiratory papillomatosis (RRP) management is advancing with new therapies and insights into human papilloma virus (HPV). Research explores HPV prevalence, immune roles, and novel treatments like lasers and cidofovir for RRP.

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Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Area of Science:

Otolaryngology
Pediatric Oncology
Virology

Background:

Recurrent respiratory papillomatosis (RRP) is a significant laryngeal neoplasm in children.
Managing RRP presents ongoing challenges due to its persistent nature.

Purpose of the Study:

To review recent advancements in understanding and managing RRP.
To highlight emerging therapeutic options and research findings.

Main Methods:

Literature review of recent investigations into RRP.
Analysis of studies on human papilloma virus (HPV) and RRP pathogenesis.
Evaluation of novel treatment modalities.

Main Results:

Updated prevalence data for HPV in women.
Links between socioeconomic status and RRP severity.
Insights into HPV's malignant potential in head and neck cancers.
The role of the immune system and cyclooxygenase-2 in RRP.
Efficacy of HPV vaccination, pulsed dye/KTP laser therapy, and cidofovir.
Potential of specific lasers and cidofovir in RRP treatment.

Conclusions:

RRP management is dynamic, with new therapies offering improved control.
Despite advancements, RRP remains a high-morbidity disease.
The shift towards prevention requires long-term evaluation; further research is essential.