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Related Concept Videos

Rabies01:28

Rabies

Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...
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Respiratory Syncytial Virus Disease

Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...
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Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
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Viral hepatitis is an inflammatory condition of the liver caused by infection with hepatotropic viruses, most commonly hepatitis A, B, C, D, and E. Despite variations in structure and transmission, all viruses mentioned infect hepatocytes and provoke immune responses that can hinder liver function. Additionally, some non-hepatotropic viruses can also lead to hepatic inflammation.Hepatitis A VirusHepatitis A virus (HAV) is transmitted through the fecal–oral route, typically by ingestion of food...
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Acute Kidney Injury II: Pathophysiology

Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
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Updated: Jun 28, 2026

Viral Tracing of Genetically Defined Neural Circuitry
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Published on: October 17, 2012

Viral rhabdomyolysis.

Sucharitha Shanmugam1, Mythili Seetharaman

  • 1Department of Medicine, Albert Einstein Medical Center, Philadelphia, PA, USA. seetharm@einstein.edu

Southern Medical Journal
|November 14, 2008
PubMed
Summary

Herpes simplex virus infection can cause severe muscle breakdown (rhabdomyolysis) and acute kidney injury. This case highlights the potential for viral infections to lead to life-threatening conditions.

Area of Science:

  • Virology
  • Neurology
  • Nephrology

Background:

  • Virus-induced myopathy is a recognized cause of rhabdomyolysis.
  • Rhabdomyolysis involves severe muscle damage and can lead to kidney failure.

Observation:

  • A 30-year-old patient presented with symptoms of rhabdomyolysis.
  • The patient was diagnosed with a herpes simplex virus infection.

Findings:

  • The patient developed acute renal failure concurrently with rhabdomyolysis.
  • Herpes simplex virus infection was identified as the likely cause of the patient's condition.

Implications:

  • This case underscores the importance of considering viral etiologies in patients presenting with rhabdomyolysis and acute kidney injury.

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  • Early diagnosis and management of viral infections may prevent severe complications like rhabdomyolysis and renal failure.
  • Highlights the potential for herpes simplex virus to cause severe systemic illness beyond typical presentations.