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[New method of multi-components quantitation by one marker new method for quality evaluation of Guanmaikang capsula]
Gui-xin Zou1, Xian-min You, Ying Zhang
1Liaoning Academy of Traditional Chinese Medicine, Shenyang 110034, China.
Objective:
To establish a new quality evaluation method for traditional Chinese medicine preparations, using one chemical reference substance to calcutate multi-components simultaneously.
Method:
Employed puerarin as the maker component, puerarin relative correction factors (RCF) of salvianolic acid B to puerarin and paidzein to puerarin were calcatated in the chromatographic conditions for determination of the three components in Guanmaikang capsules. The contents of Puerarin were determined by external standard method, and those of salvianolic acid B and paidzein were calculated by puerarin and their RCF. The accuracy of the new method was evaluated by comparing the calculated contents with the determined.
Result:
The analysis methods were established, and it has been no significant difference between the calculated contents and determined contents.
Conclusions:
The method can control the components without providing salvianolic acid B and paidzein reference. It is to be a suitable quality evaluation pattern for TCM Preparation.
