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Related Concept Videos

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies01:27

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
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Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
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Pulmonary Function Tests01:25

Pulmonary Function Tests

Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
Pulmonary Hypertension: Classification and Pathogenesis01:30

Pulmonary Hypertension: Classification and Pathogenesis

Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
There are various classifications for PH, each relating to different underlying causes and also...
Other Pulmonary Disorders01:17

Other Pulmonary Disorders

Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
COPD: Pathogenesis and Clinical Features01:20

COPD: Pathogenesis and Clinical Features

Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...

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Updated: Jun 28, 2026

Generation of Human 3D Lung Tissue Cultures (3D-LTCs) for Disease Modeling
05:47

Generation of Human 3D Lung Tissue Cultures (3D-LTCs) for Disease Modeling

Published on: February 12, 2019

[Basic research in pulmonology].

Joaquim Gea1

  • 1Servicio de Neumología-URMAR, Hospital del Mar-IMIM, Departament CEXS, Universitat Pompeu Fabra, CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Barcelona, España. jgea@imim.es

Archivos De Bronconeumologia
|November 15, 2008
PubMed
Summary
This summary is machine-generated.

This review highlights recent basic science articles on respiratory diseases. Key topics include chronic obstructive pulmonary disease, asthma, lung cancer, and pulmonary fibrosis, emphasizing inflammation, oxidative stress, and novel therapies.

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Published on: February 12, 2019

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Bronchoalveolar Lavage (BAL) for Research; Obtaining Adequate Sample Yield
11:47

Bronchoalveolar Lavage (BAL) for Research; Obtaining Adequate Sample Yield

Published on: March 24, 2014

Area of Science:

  • Pulmonary Medicine
  • Basic Science Research
  • Respiratory System

Context:

  • Recent publications in Archivos de Bronconeumología cover fundamental research in respiratory diseases.
  • The review synthesizes key findings relevant to clinical practice and future research directions.

Purpose:

  • To provide an overview of significant basic science advancements in respiratory medicine.
  • To identify emerging trends and critical research areas within pulmonology.

Summary:

  • Articles discussed include extrapulmonary inflammation and oxidative stress in chronic obstructive pulmonary disease (COPD), bronchial remodeling, and immunoglobulin-E blockers in asthma.
  • Research on lung cancer covers gene therapy and chemotherapy resistance. Ischemia-reperfusion injury, pulmonary fibrosis biomarkers, and the role of transforming growth factor-beta were also examined.
  • Studies on sleep apnea syndrome and pulmonary infections explored oxidative stress, alongside tuberculosis diagnosis and treatment.

Impact:

  • Highlights the importance of basic science in understanding and treating complex respiratory conditions.
  • Informs researchers and clinicians about cutting-edge developments in pulmonology.
  • Identifies areas for further investigation in inflammation, oxidative stress, and therapeutic interventions for lung diseases.