Huge intracardiac thrombosis in a patient on veno-arterial extracorporeal membrane oxygenation support

Florian Weis1, Andres Beiras-Fernandez, Dirk Bruegger

  • 1Department of Anesthesiology, University Hospital Grosshadern, Ludwig-Maximilians-University, Munich, Germany. Florian.Weis@med.uni-muenchen.de

Insights

Congenital hypertrophic obstructive cardiomyopathy (HOCM) patients undergoing TASH and AICD implantation may face acute heart failure and severe cardiac thrombosis, even with anticoagulation.

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Critical Care Medicine

Background:

  • Congenital hypertrophic obstructive cardiomyopathy (HOCM) presents significant challenges in heart failure management.
  • Transcoronary ablation of the septal hypertrophy (TASH) and automated cardioverter/defibrillator (AICD) implantation are therapeutic options for symptomatic HOCM.

Observation:

  • A young woman with HOCM experienced acute heart failure post-TASH and AICD implantation.
  • The patient required veno-arterial extracorporeal membrane oxygenation (VA-ECMO) support.
  • Near-complete thrombosis of cardiac chambers developed despite therapeutic anticoagulation.

Findings:

  • Perioperative acute heart failure is a potential complication following TASH and AICD procedures in HOCM.
  • Severe intra-cardiac thrombosis can occur in the context of VA-ECMO and anticoagulation therapy.
  • The interplay between HOCM, surgical interventions, and anticoagulation requires further investigation.

Implications:

  • This case highlights the critical need for vigilant monitoring for thrombosis in HOCM patients post-intervention.
  • Optimal anticoagulation strategies in patients with HOCM on VA-ECMO warrant further research.
  • Understanding and mitigating perioperative complications are crucial for improving outcomes in HOCM management.

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