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Related Experiment Video

Updated: Jun 28, 2026

Fingerprinting Cardiolipin in Leukocytes by Mass Spectrometry for a Rapid Diagnosis of Barth Syndrome
06:48

Fingerprinting Cardiolipin in Leukocytes by Mass Spectrometry for a Rapid Diagnosis of Barth Syndrome

Published on: March 23, 2022

Papillon-Lefevre syndrome: a case report.

P Subramaniam1, S Mathew, K K Gupta

  • 1Department of Pedodontics and Preventive Dentistry, The Oxford Dental College, Hospital and Research Centre, Bommanahalli, Hosur Road, Bangalore - 560 068, Karnataka, India. drpriyapedo@yahoo.com

Journal of the Indian Society of Pedodontics and Preventive Dentistry
|November 15, 2008
PubMed
Summary
This summary is machine-generated.

Papillon-Lefevre syndrome, a rare genetic disorder, causes severe palmoplantar hyperkeratosis and early tooth loss. This case report details the prosthodontic rehabilitation of a 15-year-old patient with this condition.

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Last Updated: Jun 28, 2026

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06:48

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Published on: March 23, 2022

Area of Science:

  • Dentistry
  • Genetics
  • Oral Medicine

Background:

  • Papillon-Lefevre syndrome is a rare autosomal recessive disorder.
  • Characterized by palmoplantar hyperkeratosis and severe, rapidly progressing periodontitis.
  • Leads to premature loss of both primary and permanent teeth, often resulting in early edentulism.

Observation:

  • A case report focusing on a 15-year-old female patient diagnosed with Papillon-Lefevre syndrome.
  • The patient presented with the characteristic clinical manifestations of the syndrome.

Findings:

  • The report details the prosthodontic rehabilitation process for the patient.
  • Focuses on restoring function and aesthetics in a young patient with extensive tooth loss.

Implications:

  • Highlights the importance of comprehensive prosthodontic management in Papillon-Lefevre syndrome.
  • Provides insights into managing early-onset edentulism due to rare genetic disorders.
  • Emphasizes the multidisciplinary approach required for such complex cases.