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Further evidence of spontaneous cure in human Chagas disease

João Carlos Pinto Dias1, Emmanuel Dias, Olindo Assis Martins-Filho

  • 1Fundação Oswaldo Cruz, Belo Horizonte, MG. jcpdias@cpqrr.fiocruz.br

Revista Da Sociedade Brasileira De Medicina Tropical
|November 15, 2008
PubMed

An acute case of Chagas disease was studied in 1944, with clinical and laboratory follow-up until 2007, in Bambuí, Minas Gerais, Brazil. A five-year-old girl living in a rural hut that was highly infested with Triatoma infestans presented a febrile clinical condition compatible with the acute form of trypanosomiasis. She presented a positive thick blood smear, but never again showed serological and/or parasitological evidence of Trypanosoma cruzi infection, on several occasions. This patient never received any specific treatment and, to this day, she remains completely asymptomatic, with normal findings from clinical, electrocardiographic, X-ray and echocardiographic examinations.

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