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Updated: Jun 28, 2026

A Patient-Derived Xenograft Model for Venous Malformation
Published on: June 15, 2020
Clinical characteristic of spinal vascular malformation in pediatric patients
Jianxin Du1, Feng Ling, Ming Chen
1Department of Neurological Surgery, Xuanwu Hospital, Capital University of Medical Sciences, Beijing, 100053, China.
Objective:
Seventy-two pediatric spinal vascular malformation cases were reviewed and the characteristics of their clinical symptoms, diagnoses, and therapies were analyzed.
Materials And Methods:
A thorough overview was compiled examining patient sex, age, location, history, development, treatment, clinical, and anatomical results.
Results:
Spinal cord arteriovenous malformation was the most common (44.4%) subtype to be seen in these pediatric patients, while subdural perimedullary arteriovenous fistula (23.6%) was the second, followed by Cobb's syndrome (13.9%) and intramedullary cavernous angioma (5.6%). No spinal dual arteriovenous fistulae were found in infants. The highest incidence was seen during the infant and adolescent periods. Sixty-nine cases were treated by surgeries, embolizations, or a combination of both, and 71.5% of them had improved.
Conclusions:
Early diagnosis and treatment are required. Surgery and embolization, or a combination of the two, are the current candidates for treatment.
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