Related Experiment Videos
[Confusion and unexplained fever in an elderly man: a case report]
Revue Medicale De Liege
|November 18, 2008
Summary
A positive PCR for herpes virus confirmed herpes virus meningoencephalitis in an 81-year-old man presenting with confusion and hyperthermia. Temporal lobe necrosis on CT scan highlighted this severe neurologic emergency.
Area of Science:
- Neurology
- Infectious Diseases
- Neuroimaging
Background:
- Herpes virus meningoencephalitis is a rare but severe neurological emergency.
- Early diagnosis and treatment are crucial for patient outcomes.
Observation:
- An 81-year-old male presented with confusion and unexplained hyperthermia.
- Initial examinations, including CT scan and lumbar puncture, were inconclusive.
- Meningeal signs were absent.
Findings:
- Polymerase Chain Reaction (PCR) for herpes virus returned highly positive.
- Cerebral CT scan revealed temporal lobe necrosis, characteristic of herpes virus meningoencephalitis.
Implications:
- This case underscores the importance of considering herpes virus meningoencephalitis in elderly patients with atypical neurological presentations.
- Advanced diagnostic techniques like PCR are vital for timely diagnosis.
- Prompt recognition and management of this condition can prevent severe neurological sequelae.
Related Concept Videos
Increased Body Temperature
A body temperature above 38°C (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in response to an infection or illness.
Types of Fever
Fever can be triggered by several factors, including infections, nervous system disorders, certain cancers, blood diseases like leukemia, embolism, thrombosis, heatstroke, dehydration, surgical trauma, crushing injuries, and allergic reactions.
Here are the different types of fever:
Here are the different types of fever:
Patterns of Fever
Before understanding the types and patterns of fever, it is essential to know its phases.
Rocky Mountain Spotted Fever
Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
Methods of reducing fever
The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
Pharmacological Methods of Reducing Fever:
Encephalitis l: Introduction
Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...