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Alterations in Glucose Disposal in Sleep-disordered Breathing

Naresh M Punjabi1, Brock A Beamer

  • 1Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. npunjabi@jhmi.edu

American Journal of Respiratory and Critical Care Medicine
|November 18, 2008
PubMed
Summary

Sleep-disordered breathing (SDB) significantly impairs insulin sensitivity and pancreatic beta-cell function, independent of body fat. These metabolic defects increase the risk for glucose intolerance and type 2 diabetes mellitus in individuals with SDB.

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