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Updated: Jun 28, 2026

Addressing Practical Issues in Atomic Force Microscopy-Based Micro-Indentation on Human Articular Cartilage Explants
Published on: October 28, 2022
Minced articular cartilage--basic science, surgical technique, and clinical application
Frank McCormick1, Adam Yanke, Matthew T Provencher
1Department of Orthopaedic Surgery, Naval Medical Center, San Diego, CA, USA. drfrankmccormick@yahoo.com
Abstract:
Minced articular cartilage procedures are attractive surgical approaches for repairing articular cartilage, as they are 1-staged, autologous, and inserted on a carrier that can potentially be placed arthroscopically. The principle of mincing the autologous donor cartilage is to create a larger surface area for cartilage expansion. Placement on a scaffold carrier allows for a chondro-inductive and chondro-conductive milieu. Early animal and preclinical models have demonstrated hyaline-like tissue repair. Further work needs to be conducted in this promising approach.
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