Angiosarcoma of the right atrium masquerading as recurrent pulmonary embolism

Primary cardiac angiosarcoma is a rare tumor that may present with features mimicking venous thromboembolic disease, making the diagnosis particularly challenging. Without a high index of suspicion, the majority of cases will remain undetected until the disease is advanced. As a result, the outlook for most patients remains dismal even with aggressive multimodality treatment. We report a case of angiosarcoma masquerading as recurrent pulmonary embolism successfully treated by radical surgery and adjuvant cytotoxic chemotherapy.