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Published on: August 23, 2022
Two-year-old boy with cervical and liver abscesses
Rebecca Fehon1, Sam Mehr, Erik La Hei
1Department of Infectious Diseases, Children's Hospital at Westmead, Westmead, New South Wales, Australia.
Insights
Pyogenic liver abscesses are rare in children, but common in those with chronic granulomatous disease (CGD). This case highlights CGD complications, including BCGitis and liver abscesses, managed non-surgically.
Area of Science:
- Pediatric Infectious Diseases
- Immunology
- Radiology
Background:
- Pyogenic liver abscesses are uncommon in pediatric populations.
- Chronic granulomatous disease (CGD) predisposes individuals to specific infections, including liver abscesses.
- BCG vaccination complications are increasingly recognized in CGD patients.
Observation:
- A 2-year-old boy presented with BCGitis and Staphylococcus aureus cervical adenitis.
- The patient subsequently developed pyogenic liver abscesses.
- Diagnosis of X-linked CGD was confirmed.
Findings:
- The case illustrates characteristic radiological findings of liver abscesses in CGD.
- Successful non-surgical management of liver abscesses in this CGD patient.
- Demonstrates recognized complications of BCG vaccination in CGD.
Implications:
- Highlights the importance of considering CGD in children with recurrent infections and liver abscesses.
- Emphasizes non-surgical management strategies for liver abscesses in CGD.
- Underscores the risks associated with BCG vaccination in immunocompromised children with CGD.
Abstract:
Pyogenic liver abscesses are rare in children but relatively common in those with chronic granulomatous disease (CGD). We present a case of a 2 year old boy who initially presented with BCGitis and Staphylococcus aureus cervical adenitis, and then subsequently developed liver abscesses. A diagnosis of X-linked CGD was confirmed. This case demonstrates the typical radiological features of liver abscesses in CGD, its management without surgical intervention, and the increasingly recognised complications of BCG vaccination in CGD.
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