Related Experiment Video
Updated: Jun 27, 2026

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
Published on: July 24, 2020
Optical coherence tomography diagnostic imaging
1Lantis Laser, Inc., Denville, New Jersey, USA.
Abstract:
Optical coherence tomography (OCT) is a noninvasive and nondestructive method for imaging the microstructural detail of oral tissue in situ, providing clinicians with quantitative and qualitative information. It is capable of evaluating the health of hard and soft tissue by providing a cross-sectional "optical biopsy" of tissue up to 3 mm in depth from the surface. The resultant imaging has an axial resolution of 1-10 micro, capturing structural details not possible with x-rays (and without the use of ionizing radiation). OCT imaging has the potential to detect and diagnose very early stages of disease in teeth, periodontal tissue, and mucosa. Early demineralization, remineralization, recurrent caries, tooth and restorative failures, root canals, periodontal disease, soft tissue dysplasias, and precancerous lesions can be imaged and monitored in real time on a computer monitor.
Related Concept Videos
Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies III: Computed Tomography
Imaging Studies I: CT and MRI
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Positron Emission Tomography
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...
Imaging Studies for Cardiovascular System V: CT
Imaging Biological Samples with Optical Microscopy
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...

