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Updated: Jun 27, 2026
04:57
Establishing a Competing Risk Regression Nomogram Model for Survival Data
Published on: October 23, 2020
Competing risks to breast cancer mortality in Catalonia
Ester Vilaprinyo1, Rosa Gispert, Montserrat Martínez-Alonso
1Institut d'Investigació Biomèdica de Bellvitge, IDIBELL, Hospitalet de Llobregat Catalonia, Spain. evilaprinyo@cmb.udl.cat
BMC Cancer
|November 19, 2008
Summary
Breast cancer significantly impacted mortality in Catalonia, peaking for cohorts born 1945-1954. Its influence decreased for later birth cohorts, providing data for screening intervention assessments.
Area of Science:
- Epidemiology
- Public Health
- Biostatistics
Background:
- Breast cancer mortality trends are influenced by competing risks.
- Understanding these dynamics is crucial for evaluating interventions.
Purpose of the Study:
- Assess breast cancer's impact on all-cause mortality in Catalonia by age and birth cohort.
- Estimate the risk of death from causes other than breast cancer.
Main Methods:
- Employed multi-decrement life table methodology.
- Calculated all-cause mortality probabilities by age and cohort.
- Subtracted breast cancer mortality probabilities to derive competing risk mortality.
Main Results:
- Breast cancer's mortality impact peaked for cohorts born 1945-1954 (approx. 24% of mortality in 40-49 age group).
- Impact decreased for cohorts born after 1955.
- Quantified the risk of death from competing causes.
Conclusions:
- The study quantified the effect of removing breast cancer mortality across age groups and birth cohorts.
- Results align with US findings.
- Generated estimates for competing-cause mortality to assess mammography screening effectiveness in Catalonia.
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