Related Experiment Video
Updated: Jun 27, 2026

Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats
Published on: January 21, 2020
Bone metastases mimicking Complex Regional Pain Syndrome I: a case report
Melchior Huggler1, Rudolf Kissling, Florian Brunner
1Department of Physical Medicine and Rheumatology, Balgrist University Hospital, Zurich, Switzerland. Menk.Huggler@gmx.ch
Introduction:
Since there are no valid tools available for the diagnosis of Complex Regional Pain Syndrome I, exclusion of other underlying conditions plays an important role in the diagnostic process.
Case Presentation:
A 77-year-old Caucasian man was referred with painful swelling and dysfunction of the right knee. Based on the history and clinical presentation, the referring physician assumed a case of Complex Regional Pain Syndrome I. However, after careful evaluation of the differential diagnosis, a metastatic urothelial carcinoma was diagnosed.
Conclusion:
Even if the clinical picture resembles Complex Regional Pain Syndrome I, the differential diagnosis must be evaluated carefully.
