Ultrasound assisted regioselective sulfonation of aromatic compounds with sulfuric acid
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Updated: Jun 27, 2026

Efficient Synthesis of Polyfunctionalized Benzenes in Water via Persulfate-promoted Benzannulation of α,β-Unsaturated Compounds and Alkynes
Published on: December 16, 2019
Ziyauddin S Qureshi1, Krishna M Deshmukh, Sachin R Jagtap
1Department of Chemistry, Institute of Chemical Technology, University of Mumbai, N. Parekh Marg, Matunga, Mumbai 400 019, India.
Abstract:
A simple and convenient methodology for selective sulfonation of aromatic compounds using sulfuric acid under sonication is described. The present methodology shows a considerable enhancement in the reaction rate along with improved selectivity compared with the reactions performed under silent conditions. The effect of various parameters such as agitation speed, sulfuric acid concentration, and temperature on reaction system have been investigated and are explained on the basis of ultrasonically generated cavitational effects.
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