Development and validation of a self-administered Food Allergy Quality of Life Questionnaire for children

B M J Flokstra-de Blok1, A DunnGalvin, B J Vlieg-Boerstra

  • 1Department of Paediatrics, Division of Paediatric Pulmonology and Paediatric Allergy, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. b.m.j.flokstra.de.blok@bkk.umcg.nl

Insights

A new questionnaire, the Food Allergy Quality of Life Questionnaire–Child Form (FAQLQ-CF), effectively measures health-related quality of life in children with food allergies. This validated tool is easy to use and aids in clinical research.

Area of Science:

  • Pediatric Allergy and Immunology
  • Health-Related Quality of Life (HRQL) Research
  • Psychometrics and Questionnaire Development

Background:

  • Food allergies significantly impact children's health-related quality of life (HRQL).
  • A validated, self-administered, disease-specific HRQL questionnaire for pediatric food allergy was previously unavailable.
  • Addressing this gap is crucial for accurate assessment and research in pediatric food allergy.

Purpose of the Study:

  • To develop and validate the Food Allergy Quality of Life Questionnaire–Child Form (FAQLQ-CF) in Dutch.
  • To create a reliable and disease-specific instrument for assessing HRQL in children with food allergies.
  • To provide a tool for use in clinical research and practice.

Main Methods:

  • Generated 139 HRQL items through interviews with 13 food-allergic children (aged 8-12).
  • Identified key items using the clinical impact method with 51 food-allergic children, resulting in the 24-item FAQLQ-CF.
  • Validated the FAQLQ-CF cross-sectionally using 115 food-allergic children, comparing it with the FAIM and CHQ-CF87.

Main Results:

  • Demonstrated construct validity through significant correlation between FAQLQ-CF and FAIM (rho=0.60).
  • Achieved excellent internal consistency (Cronbach's alpha=0.94) and discriminated based on the number of food allergies.
  • Showed convergent/discriminant validity by correlating with 8 of 11 CHQ-CF87 sub-scales.

Conclusions:

  • The FAQLQ-CF is the first self-administered, disease-specific HRQL questionnaire for food-allergic children.
  • The questionnaire exhibits strong internal consistency and cross-sectional validity.
  • The FAQLQ-CF is a potentially valuable tool for clinical research due to its validity, ease of use, and ability to differentiate patient groups.
Abstract