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Cough-type asthma: a review
E J O'Connell1, A R Rojas, M I Sachs
1Section of General Pediatrics and Pediatric Allergy and Immunology, Mayo Clinic, Rochester, Minnesota.
Annals of Allergy
|April 1, 1991
Summary
Cough-variant asthma presents as a chronic cough, often worsened by exercise or infections. Diagnosis involves bronchial provocation, and treatment typically includes bronchodilators, with potential progression to classical asthma.
Area of Science:
- Pulmonology
- Allergy and Immunology
Background:
- Cough-variant asthma is a distinct clinical entity characterized by chronic, nonproductive cough.
- Symptoms are frequently triggered by exercise and upper respiratory tract infections.
Purpose of the Study:
- To outline the diagnostic approaches and therapeutic strategies for cough-variant asthma.
- To describe the natural history and potential progression of this condition.
Main Methods:
- Review of clinical presentation and diagnostic criteria for cough-variant asthma.
- Discussion of therapeutic options including bronchodilators, cromolyn sodium, and inhaled corticosteroids.
Main Results:
- Bronchial provocation maneuvers are key diagnostic tools for older children and adults.
- A significant proportion (33-50%) of patients may develop classical asthma with wheezing over time.
Conclusions:
- Cough-variant asthma is a recognizable condition requiring specific diagnostic and management approaches.
- Early recognition and treatment may influence the progression to more severe asthma phenotypes.