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Updated: Jun 27, 2026

Pediatric Animal Model of Extracorporeal Cardiopulmonary Resuscitation After Prolonged Circulatory Arrest
Published on: May 26, 2023
Systemic hyperkalemia for cardiac arrest on CPB with or without cross-clamping
Tharumenthiran Ramanathan1, Prem Shekar, Daniel Fitzgerald
1Division of Cardiac Surgery, Brigham and Women's Hospital, Boston, Massachusetts 02215, USA.
Abstract:
Myocardial protection may be compromised in situations with a patent left internal mammary artery (LIMA) graft or an unclamped aorta. Because of collateral coronary blood flow, electrical arrest may not be achieved. Currently, hypothermia is often used to augment myocardial protection and provide cardiac arrest in these situations. We report a simple, novel technique of systemic hyperkalemia during cardiopulmonary bypass to achieve rapid and complete electromechanical arrest. By providing complete diastolic arrest, uniform myocardial protection is ensured.
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