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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...

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Related Experiment Videos

Nodular 'fasciitis' presenting as a cutaneous polyp.

Tim S Bracey1, Simon Wharton, Mark E F Smith

  • 1Department of Histopathology, Derriford Hospital, Plymouth, UK. timbracey@doctors.net.uk

Journal of Cutaneous Pathology
|November 20, 2008
PubMed
Summary

This study describes a rare polypoid skin form of nodular fasciitis in a child. This finding expands the known clinical presentations of this benign myofibroblastic tumor.

Related Experiment Videos

Area of Science:

  • Dermatopathology
  • Pediatric Oncology
  • Soft Tissue Tumors

Background:

  • Nodular fasciitis is a benign myofibroblastic proliferation.
  • It can be clinically misdiagnosed as sarcoma due to rapid growth.
  • While typically involving fascia, rare cutaneous variants exist.

Observation:

  • A case of a polypoid cutaneous nodular fasciitis on the upper arm of an 8-year-old girl is presented.
  • This specific presentation is rare within the spectrum of nodular fasciitis.
  • The lesion exhibited rapid growth, a characteristic feature of nodular fasciitis.

Findings:

  • This report details the first known case of a polypoid dermal variant of nodular fasciitis.
  • Histopathological confirmation is crucial for differentiating from malignant neoplasms.
  • The case highlights the diverse clinical appearances of nodular fasciitis.

Implications:

  • This finding broadens the differential diagnosis for pediatric skin lesions.
  • Awareness of this variant aids in accurate clinical and pathological diagnosis.
  • It contributes to understanding the full spectrum of nodular fasciitis presentations.