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A Preclinical Model of Exertional Heat Stroke in Mice
Published on: July 1, 2021
Multiple Organ Failure Following Near Fatal Exertional Heat Stroke
Maximo H Trujillo1, Ezequiel Bellorin-Font, Carlos F Fragachan
1Critical Care Units and Division of Nephrology, The University Hospital of Caracas, Caracas, Venezuela. maxtrujillo@movistar.net.ve
Abstract:
We describe the clinical features of a patient with near-fatal heat stroke who was admitted to our intensive care unit. A 14-year-old girl became convulsive and hyperthermic when participating in a strenuous hike under direct sunlight in a hilly area in Venezuela on a very hot and humid day. During the following days, she developed multiple organ failure, including neurological impairment, acute renal failure, disseminated intravascular coagulation, and extensive hepatic and muscle damage. Treatment consisted of ventilatory support, hemodialysis, corticosteroids, and enteral nutrition. This case of multiple organ failure following near-fatal heat stroke illustrates that although there are no specific techniques and measures for the treatment of this condition, intensive care management and conservative strategies can result in patient survival and complete recovery.
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