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Cardiac tamponade and pleural effusion complicating varicella: a case report
Syed Asif Masood1, Ernest Kiel, Olugbenga Akingbola
1Department of Pediatrics, Louisiana State University, Shreveport, LA 71103, USA. masoodsa@ihs.org
Insights
Varicella infection can rarely cause severe complications like cardiac tamponade and pleural empyema in infants. This case highlights the importance of recognizing and managing these uncommon, serious pediatric varicella complications.
Area of Science:
- Pediatrics
- Infectious Diseases
- Cardiology
Background:
- Varicella (chickenpox) is typically a mild childhood illness.
- Serious complications, though rare, can occur, particularly in high-risk groups.
- Cardiac tamponade due to varicella-associated pericardial effusion is exceptionally infrequent.
Observation:
- An 8-month-old infant developed cardiac tamponade due to purulent bacterial pericardial effusion following varicella infection.
- The infant also experienced pleural empyema, another uncommon complication of varicella.
- Management involved a pericardial window formation and thoracostomy drainage.
Findings:
- This case highlights the potential for severe cardiac and pulmonary complications following varicella infection, even in infants.
- Bacterial superinfection of pericardial effusion leading to cardiac tamponade is a critical, albeit rare, sequela.
- Pleural empyema represents another serious, uncommon complication requiring surgical intervention.
Implications:
- Clinicians should maintain a high index of suspicion for severe complications in infants presenting with varicella, especially with cardiac or respiratory symptoms.
- Early recognition and aggressive management are vital for improving outcomes in varicella-related cardiac tamponade and empyema.
- Further review of literature is needed to fully understand the incidence and management of varicella-associated pericarditis and its complications.
Abstract:
Varicella is a common infectious disease, usually benign and self-limited, and complications are believed to be rare. Most cases occur in healthy children younger than 14 years. Serious complications are uncommon, although high-risk groups have been identified, such as immunosuppressed patients, neonates, and adults. Cardiac tamponade after pericardial effusion occurring as a complication of varicella infection has been very infrequently reported. We describe an 8-month-old infant presenting with cardiac tamponade after varicella infection secondary to purulent bacterial pericardial effusion. He required a pericardial window formation. He also developed pleural empyema, another uncommon complication requiring thoracostomy drainage. This illustrative case, management, and unique features will be presented along with a review of all cases of varicella complicated by pericarditis in the English literature.
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