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Published on: May 26, 2023

Microbial risk factors of cardiovascular and cerebrovascular diseases: potential therapeutical options

Mohammed Abdalla Abbas1, Albrecht Guenther, Sebastiano Galantucci

  • 1Neurology Department, Sohag Faculty of Medicine, Sohag University, Sohag, Egypt.

The Open Neurology Journal
|November 20, 2008
PubMed

Insights

Chronic infections and inflammation are linked to atherosclerosis development. Assessing infection markers can identify patients at high risk for vascular events, guiding aggressive treatment strategies.

Area of Science:

  • Cardiovascular Medicine
  • Infectious Diseases
  • Immunology

Background:

  • Atherosclerosis pathogenesis is increasingly linked to infection and inflammation.
  • Growing evidence suggests a role for chronic infections in atherogenesis.
  • Inflammatory processes are central to the development of atherosclerotic plaques.

Purpose of the Study:

  • To explore the role of infection and inflammation in atherosclerosis.
  • To evaluate the utility of serological and inflammatory markers in risk assessment.
  • To identify patient groups benefiting from intensified vascular event prevention strategies.

Main Methods:

  • Review of existing literature on infection, inflammation, and atherosclerosis.
  • Analysis of serological markers indicative of chronic infection.
  • Assessment of inflammatory markers associated with cardiovascular risk.

Main Results:

  • Significant association found between chronic infection markers and atherosclerosis.
  • Inflammatory markers correlate with increased risk of vascular events.
  • Serological assessment aids in identifying high-risk individuals.

Conclusions:

  • Infection and inflammation play a critical role in atherosclerosis development.
  • Serological and inflammatory markers are valuable adjuncts for risk stratification.
  • Early identification of high-risk patients can optimize treatment and outcomes.
Keywords:
Chlamydia pneumoniaeCytomegalovirusHelicobacter pyloriStrokeantibioticsatherosclerosisinfectionodontopathogensrisk factorstherapy

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