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Related Concept Videos

Gene-Environment Interactions01:20

Gene-Environment Interactions

Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...
Background and Environment Affect Phenotype02:27

Background and Environment Affect Phenotype

Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
Causes of Social Behavior III: Biological and Environmental Influences01:28

Causes of Social Behavior III: Biological and Environmental Influences

Social behavior is a complex phenomenon that arises from the interaction between biological predispositions and environmental influences. This intricate interplay shapes how individuals think, feel, and act in various social contexts. Understanding these mechanisms requires insights from psychology, neuroscience, genetics, and evolutionary theory.Environmental Influences on Social BehaviorEnvironmental factors, including temperature, odors, and visual stimuli, play a crucial role in shaping...
Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...
Human Genetics01:28

Human Genetics

Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
Behavioral Genetics and Its Designs01:23

Behavioral Genetics and Its Designs

Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...

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Vinyl Chloride and High-Fat Diet as a Model of Environment and Obesity Interaction
09:15

Vinyl Chloride and High-Fat Diet as a Model of Environment and Obesity Interaction

Published on: January 12, 2020

Gene-environment interaction and obesity.

Lu Qi1, Young Ae Cho

  • 1Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA. nhlqi@channing.harvard.edu

Nutrition Reviews
|November 21, 2008
PubMed
Summary
This summary is machine-generated.

Obesity is driven by genetics and environment. Understanding gene-environment interactions can personalize obesity prevention strategies for better public health outcomes.

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Segmentation and Measurement of Fat Volumes in Murine Obesity Models Using X-ray Computed Tomography

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Last Updated: Jun 27, 2026

Vinyl Chloride and High-Fat Diet as a Model of Environment and Obesity Interaction
09:15

Vinyl Chloride and High-Fat Diet as a Model of Environment and Obesity Interaction

Published on: January 12, 2020

Gene-environment Interaction Models to Unmask Susceptibility Mechanisms in Parkinson's Disease
08:09

Gene-environment Interaction Models to Unmask Susceptibility Mechanisms in Parkinson's Disease

Published on: January 7, 2014

Segmentation and Measurement of Fat Volumes in Murine Obesity Models Using X-ray Computed Tomography
13:09

Segmentation and Measurement of Fat Volumes in Murine Obesity Models Using X-ray Computed Tomography

Published on: April 4, 2012

Area of Science:

  • Public Health
  • Genetics
  • Nutrition Science

Background:

  • Obesity epidemic is a significant global health concern.
  • Common obesity results from complex interactions between genetic predisposition and environmental factors.
  • Key environmental drivers include high-energy diets, low-fiber food consumption, and sedentary lifestyles.

Purpose of the Study:

  • To review recent advancements in identifying genetic and environmental risk factors for obesity.
  • To examine the evidence for gene-environment interactions in obesity development.
  • To highlight the potential for personalized obesity prevention strategies.

Main Methods:

  • Review of epidemiological studies on obesity risk factors.
  • Analysis of genome-wide association studies (GWAS) identifying obesity-related genes (e.g., FTO, MC4R).
  • Examination of evidence from observational studies and randomized intervention trials on gene-environment interactions.

Main Results:

  • Identification of specific genes (e.g., fat mass and obesity associated gene, melanocortin-4 receptor gene) linked to obesity risk.
  • Evidence supports significant gene-environment interactions influencing obesity.
  • Lifestyle and dietary factors interact with genetic predispositions.

Conclusions:

  • Personalized obesity prevention requires understanding the interplay between an individual's genetic makeup and environmental exposures.
  • Tailoring interventions based on gene-environment interactions may enhance prevention efficacy.
  • Further research into gene-environment interactions is crucial for combating the obesity epidemic.