Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jun 27, 2026

Measurement & Analysis of the Temporal Discrimination Threshold Applied to Cervical Dystonia

Measurement & Analysis of the Temporal Discrimination Threshold Applied to Cervical Dystonia

Published on: January 27, 2018

Temporal filtering by prefrontal neurons in duration discrimination.

Ken-ichi Oshio¹, Atsushi Chiba, Masahiko Inase

¹Department of Physiology, Kinki University School of Medicine, Ohno-Higashi 377-2, Osaka-Sayama, Osaka 589 8511, Japan. oshio@med.kindai.ac.jp

The European Journal of Neuroscience

|November 21, 2008

Summary

The prefrontal cortex (PFC) plays a role in time perception. Our study shows PFC neurons exhibit temporal filtering, aiding in duration discrimination tasks.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Neuronal activity in the monkey prefrontal cortex during a duration discrimination task with visual and auditory cues.

Scientific reports·2021

Same author

Locomotor kinematics and EMG activity during quadrupedal versus bipedal gait in the Japanese macaque.

Journal of neurophysiology·2019

Same author

A high-throughput sequence analysis of Japanese patients revealed 11 candidate genes associated with type 1 autoimmune pancreatitis susceptibility.

Biochemistry and biophysics reports·2017

Same author

Unruptured cystic artery pseudoaneurysm accompanied by Mirizzi syndrome: a report of a case.

Clinical journal of gastroenterology·2015

Same author

Neuronal representation of duration discrimination in the monkey striatum.

Physiological reports·2015

Same author

Effects of pulsed magnetic stimulation on isolated crayfish heart.

Electromagnetic biology and medicine·2014

Area of Science:

Neuroscience
Cognitive Science

Background:

Neural imaging suggests the prefrontal cortex (PFC) is involved in time perception.
The specific functional roles of the PFC in time perception remain unclear.

Purpose of the Study:

To investigate the functional role of the PFC in duration discrimination.
To analyze single-neuron activity in the PFC during a time perception task.

Main Methods:

Two monkeys performed a duration-discrimination task with visual cues (0.2–2.0 s).
Single-neuron activity was recorded from the PFC during task performance.
Neuronal activity patterns (phasic, ramping, sustained) were classified.

Main Results:

Phasic neuronal activity was the most prevalent pattern in the PFC.

More Related Videos

Eye Movements in Visual Duration Perception: Disentangling Stimulus from Time in Predecisional Processes

Eye Movements in Visual Duration Perception: Disentangling Stimulus from Time in Predecisional Processes

Published on: January 19, 2024

A Two-interval Forced-choice Task for Multisensory Comparisons

A Two-interval Forced-choice Task for Multisensory Comparisons

Published on: November 9, 2018

Related Experiment Videos

Last Updated: Jun 27, 2026

Measurement & Analysis of the Temporal Discrimination Threshold Applied to Cervical Dystonia

Measurement & Analysis of the Temporal Discrimination Threshold Applied to Cervical Dystonia

Published on: January 27, 2018

Eye Movements in Visual Duration Perception: Disentangling Stimulus from Time in Predecisional Processes

Eye Movements in Visual Duration Perception: Disentangling Stimulus from Time in Predecisional Processes

Published on: January 19, 2024

A Two-interval Forced-choice Task for Multisensory Comparisons

A Two-interval Forced-choice Task for Multisensory Comparisons

Published on: November 9, 2018

Peak firing times of phasic activity were broadly distributed around 0.8 s post-cue onset.

The most frequent peak times aligned with the duration separating short and long cues.

Conclusions:

The PFC contributes to duration discrimination through temporal filtering mechanisms.
Phasic PFC activity may act as a filter, estimating cue duration.
The distribution of peak activity suggests preparation for various filtering durations.