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Updated: Jun 27, 2026

Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination
Published on: September 12, 2016
Inflammatory demyelinating neuropathies and neuropathies associated with monoclonal gammopathies: treatment update
Andreas J Steck1, Adam Czaplinski, Susanne Renaud
1Department of Neurology, University of Basel, Basel, Switzerland. asteck@uhbs.ch
Abstract:
This review focuses on recent data regarding inflammatory demyelinating neuropathies and neuropathies associated with monoclonal gammopathies. We describe both acute and chronic inflammatory neuropathies, and we discuss conditions ranging from mostly cell-mediated to antibody-mediated disorders. These diseases are characterized by proximal and distal sensory motor involvement. Treatments are based on immune-modulation and/or immune-suppression. Work-up sequence and therapeutical modes are discussed in the light of recently published data, with a special interest on new treatment modalities.
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