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Cerebral pathology in pseudoseizures.

P T Lelliott1, P Fenwick

  • 1Greenwich District Hospital, London, England.

Acta Neurologica Scandinavica
|February 1, 1991
PubMed
Summary
This summary is machine-generated.

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Pseudoseizures occurred in 17% of epilepsy unit admissions, with 42% having concurrent epilepsy. Differentiating between epileptic and pseudoseizures is challenging, even with cerebral pathology.

Area of Science:

  • Neurology
  • Psychiatry

Background:

  • Pseudoseizures (psychogenic non-epileptic seizures) are often diagnosed in epilepsy units.
  • Concurrent epilepsy is common in patients presenting with pseudoseizures.

Purpose of the Study:

  • To investigate the prevalence of pseudoseizures in an epilepsy unit.
  • To examine the overlap between pseudoseizures and epilepsy.
  • To assess cognitive deficits and EEG findings in patients with pseudoseizures.

Main Methods:

  • Retrospective analysis of 5-year admissions to a psychiatric hospital's epilepsy unit.
  • Comparison of patients with pseudoseizures (with and without concurrent epilepsy) to a control group with anxiety and affective disorders.
  • Assessment of memory deficits and electroencephalogram (EEG) abnormalities.

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Main Results:

  • 17% of admissions had pseudoseizures; 42% of these also had epilepsy.
  • Memory deficits were prevalent in 50% of pseudoseizure-only patients and 62% of those with concurrent epilepsy.
  • EEG abnormalities were more common in pseudoseizure groups compared to controls, with paroxysmal events being more frequent in concurrent epilepsy cases.

Conclusions:

  • Pseudoseizures are a significant diagnosis within epilepsy units, often co-occurring with epilepsy.
  • Cognitive deficits, particularly memory impairments, are common in patients with pseudoseizures.
  • EEG findings alone are insufficient to reliably differentiate between epileptic seizures and pseudoseizures, especially in complex cases.