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Impact of respiratory syncytial virus in the United States

Renee F Robinson1

  • 1Critical Care Systems, Inc., 705 F Lakeview Plaza Blvd., Worthington, OH 43085, USA. rrobinson@criticalcaresystems.com

American Journal of Health-System Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists
|December 5, 2008
PubMed

Insights

Respiratory syncytial virus (RSV) causes common childhood infections, leading to significant hospitalizations and long-term respiratory issues. This virus remains a leading cause of infant viral deaths despite decreased mortality rates.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Public Health

Background:

  • Respiratory syncytial virus (RSV) is a prevalent respiratory pathogen in infants and young children.
  • Nearly all children experience RSV infection by age two.
  • RSV is a primary cause of bronchiolitis and pneumonia in infants.

Purpose of the Study:

  • To summarize the impact of RSV infection on infants and young children.
  • To highlight the disease burden, complications, and economic impact of RSV.

Main Methods:

  • Literature review of RSV epidemiology and clinical impact.
  • Analysis of hospitalization data and associated costs.
  • Review of long-term respiratory sequelae in affected children.

Main Results:

  • RSV is the leading cause of viral lower respiratory tract infections in children under one.
  • RSV accounts for 75,000-125,000 US hospitalizations annually.
  • Hospitalized infants face increased risks of childhood asthma and wheezing.

Conclusions:

  • RSV infection imposes a substantial disease and economic burden on young children.
  • RSV is the primary cause of viral deaths in infants.
  • Despite reduced mortality, RSV remains a critical public health concern for pediatric respiratory health.
Abstract

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