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Related Experiment Video

Updated: Jun 27, 2026

Use of Interferon-γ Enzyme-linked Immunospot Assay to Characterize Novel T-cell Epitopes of Human Papillomavirus

Use of Interferon-γ Enzyme-linked Immunospot Assay to Characterize Novel T-cell Epitopes of Human Papillomavirus

Published on: March 8, 2012

New quadrivalent HPV vaccine developments.

John M Tovar¹, Oralia V Bazaldua

¹Feik School of Pharmacy, University of Incarnate Word, San Antonio, TX 78209, USA. jmtovar@uiwtx.edu

Postgraduate Medicine

|November 21, 2008

Summary

The human papillomavirus (HPV) vaccine prevents cervical, vulvar, and vaginal cancers, and genital warts. Post-vaccination syncope is common, so patients should remain seated and observed for 15 minutes after vaccination.

Area of Science:

Oncology
Immunology
Public Health

Background:

Human papillomavirus (HPV) infection is the most common sexually transmitted disease globally.
HPV is a primary cause of cervical, vulvar, and vaginal cancers, and genital warts.
An HPV vaccine targeting types 6, 11, 16, and 18 has been available since 2006.

Purpose of the Study:

To review the efficacy and safety of the HPV vaccine.
To highlight recent approvals for preventing vulvar and vaginal cancers.
To provide guidance on managing post-vaccination adverse events.

Main Methods:

Review of available data and US Food and Drug Administration (FDA) analysis.
Assessment of vaccine efficacy for cancer and wart prevention.

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Expression and Purification of Virus-like Particles for Vaccination

Expression and Purification of Virus-like Particles for Vaccination

Published on: June 2, 2016

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Last Updated: Jun 27, 2026

Use of Interferon-γ Enzyme-linked Immunospot Assay to Characterize Novel T-cell Epitopes of Human Papillomavirus

Use of Interferon-γ Enzyme-linked Immunospot Assay to Characterize Novel T-cell Epitopes of Human Papillomavirus

Published on: March 8, 2012

Expression and Purification of Virus-like Particles for Vaccination

Expression and Purification of Virus-like Particles for Vaccination

Published on: June 2, 2016

Evaluation of reported adverse events, including Guillain-Barré syndrome and death.

Main Results:

The HPV vaccine is approved for preventing cervical cancer, precancers, genital warts, and recently, vulvar and vaginal cancers in women aged 9-26.
FDA analysis found no association between the vaccine and reported adverse events like Guillain-Barré syndrome or death.
Post-vaccination syncope is a common occurrence.

Conclusions:

The HPV vaccine is a safe and effective tool for preventing HPV-related cancers and genital warts.
Healthcare providers should monitor patients for syncope post-vaccination, ensuring they remain seated for at least 15 minutes.