Related Experiment Video
Updated: Jun 27, 2026

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
Case report: treatment of androgen deficiency in the aging male
1Tulane University, School of Medicine, New Orleans, LA 70112, USA.
Abstract:
Androgen deficiency in the aging male is a common condition affecting millions of middle-aged and elderly men. The diagnosis is made with a high index of suspicion based on symptoms, use of an easily completed questionnaire, a physical examination, and laboratory test results showing a decrease in serum testosterone levels. Treatment can be easily accomplished with injections, patches, or gels that allow transcutaneous administration of testosterone. This article will discuss the pathophysiology of androgen deficiency in aging men, the contraindications for using hormone replacement therapy, and suggestions for monitoring patients on hormone replacement therapy.
Related Concept Videos
Menopause
Disorders of the Male Reproductive System
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Adrenal Gland Disorders
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
The Effect of Aging on Tissues
Testosterone: Functions and Regulation
