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Malignant orbital schwannoma with massive intracranial recurrence
George Miliaras1, Parmenion P Tsitsopoulos, Ioannis Asproudis
1Department of Neurosurgery, Ioannina University Hospital, Ioannina, Greece.
Background:
A 62 year old male presented with progressive diplopia, left orbital pain and impairment of visual acuity.
Method And Findings:
Neuroradiological investigation disclosed an orbital tumour. The lesion was totally excised. Histopathology examination revealed a malignant peripheral nerve sheath tumour (MPNST). The tumour recurred with intracranial extension. The patient died 13 months after the initial diagnosis.
Conclusions:
To our knowledge, this is the first reported example of a massive intracranial recurrence of an orbital MPNST. The epidemiological features, clinical course and treatment of these lesions are discussed.