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Updated: Jun 27, 2026

Closure of a Patent Foramen Ovale (PFO): An Intervention Sequence
10:52

Closure of a Patent Foramen Ovale (PFO): An Intervention Sequence

Published on: December 23, 2022

Prevalence of patent foramen ovale in patients with migraine

Vijay K Sharma, Hock L Teoh, Bernard P L Chan

    Agri : Agri (Algoloji) Dernegi'Nin Yayin Organidir = the Journal of the Turkish Society of Algology
    |November 21, 2008
    PubMed

    Insights

    Cerebral embolization via a patent foramen ovale (PFO) may trigger migraines. Standardizing PFO diagnosis and functional assessment is crucial for understanding this complex migraine cause.

    Area of Science:

    • Neurology
    • Cardiology

    Background:

    • Patent foramen ovale (PFO) is a potential cause of migraine attacks.
    • The size and functional potential of PFOs are thought to influence migraine etiology.

    Discussion:

    • Methodological issues complicate the relationship between PFO and migraine.
    • Simple PFO detection in migraine patients may not confirm causality.
    • Standardization of diagnostic methods and functional grading for PFO is urgently needed.

    Key Insights:

    • The etiological role of PFO in migraine is complex and requires further investigation.
    • Current diagnostic approaches for PFO in migraineurs have limitations.
    • A unified approach to PFO assessment is necessary for effective migraine management.

    Outlook:

    • Future research should focus on standardized diagnostic protocols for PFO.
    • Developing criteria for grading PFO functional status will aid in understanding migraine pathophysiology.
    • Improved PFO evaluation could lead to more targeted migraine treatments.

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