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Updated: Jun 27, 2026

Palladium N-Heterocyclic Carbene Complexes: Synthesis from Benzimidazolium Salts and Catalytic Activity in Carbon-carbon Bond-forming Reactions
Published on: July 30, 2017
[IrCl(2)Cp*(NHC)] complexes as highly versatile efficient catalysts for the cross-coupling of alcohols and amines
Amparo Prades1, Rosa Corberán, Macarena Poyatos
1Departamento de Química Inorgánica y Orgánica, Universitat Jaume I, 12071-Castellón, Spain.
Abstract:
A comparative study on the catalytic activity of a series of [IrCl(2)Cp*(NHC)] complexes in several C-O and C-N coupling processes implying hydrogen-borrowing mechanisms has been performed. The compound [IrCl(2)Cp*(I(nBu))] (Cp*=pentamethyl cyclopentadiene; I(nBu)=1,3-di-n-butylimidazolylidene) showed to be highly effective in the cross-coupling reactions of amines and alcohols, providing high yields in the production of unsymmetrical ethers and N-alkylated amines. A remarkable feature is that the processes were carried out in the absence of base, phosphine, or any other external additive. A comparative study with other known catalysts, such as Shvo's catalyst, is also reported.
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