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Updated: Jun 27, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
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Percutaneous aortic valve implants under sedation: our initial experience.

Miles Behan1, Peter Haworth, Nevil Hutchinson

  • 1Sussex Cardiac Centre, Brighton and Sussex University Hospital NHS Trust, Eastern Road, Brighton UK, BN2 5BE.

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
|November 21, 2008
PubMed
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Percutaneous aortic valve implantation (PAVI) can be safely performed using remifentanil-based sedation. This approach may reduce procedure time and hospital stay for patients with aortic stenosis.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Anesthesiology

Background:

  • Percutaneous aortic valve implantation (PAVI) is an effective treatment for aortic stenosis, particularly in patients with comorbidities.
  • Traditional PAVI procedures often utilize general anesthesia, which carries significant risks for this patient population.

Purpose of the Study:

  • To evaluate the feasibility and outcomes of PAVI performed under remifentanil-based sedation administered by an anesthetist.
  • To compare sedation with general anesthesia for PAVI procedures.

Main Methods:

  • Twelve patients underwent CoreValve implantation via retrograde approach.
  • Procedures were visualized using fluoroscopy and aortograms.
  • Nine patients received remifentanil-based sedation; three had general anesthesia.

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Main Results:

  • No significant differences in procedural success, procedure time, or hospital stay were observed between sedation and general anesthesia groups.
  • One patient converted from sedation to general anesthesia.
  • One mortality occurred in the general anesthesia group due to respiratory complications.

Conclusions:

  • PAVI can be successfully performed in most patients under remifentanil-based sedation.
  • Sedation may lead to shorter implant procedure times, reduced high-dependency unit stays, and earlier hospital discharge.