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Related Concept Videos

Passive Diffusion: Overview and Kinetics01:17

Passive Diffusion: Overview and Kinetics

Passive diffusion is a critical process that allows small lipophilic drugs to cross the cell membrane along a concentration gradient. This mechanism's efficiency depends on four primary factors: the membrane's surface area, the drug's lipid-water partition coefficient, the concentration gradient, and the membrane's thickness.
When administered orally, drugs establish a substantial concentration gradient between the gastrointestinal (GI) lumen and the bloodstream, expediting their diffusion into...
Diffusion01:12

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Diffusion is a type of passive transport. In passive transport, a substance tends to move from an area of high concentration to an area of low concentration until the concentration is equal across the space. For example, take the diffusion of substances through the air. When someone opens a perfume bottle in a room filled with people, the perfume is at its highest concentration in the bottle and is at its lowest at the edges of the room. The perfume vapor will diffuse, or spread away, from the...
Reynolds Transport Theorem01:24

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The nature of light has been a subject of inquiry since antiquity. In the seventeenth century, Isaac Newton performed experiments with lenses and prisms and was able to demonstrate that white light consists of the individual colors of the rainbow combined together. Newton explained his optics findings in terms of a "corpuscular" view of light, in which light was composed of streams of extremely tiny particles traveling at high speeds according to Newton's laws of motion.
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Updated: Jun 27, 2026

The Diffusion of Passive Tracers in Laminar Shear Flow
08:01

The Diffusion of Passive Tracers in Laminar Shear Flow

Published on: May 1, 2018

Tutorial on diffuse light transport.

Steven L Jacques1, Brian W Pogue

  • 1Oregon Health and Science University, Portland, Oregon 97239, USA. jacquess@ohsu.edu

Journal of Biomedical Optics
|November 22, 2008
PubMed
Summary
This summary is machine-generated.

This tutorial introduces diffuse light transport equations for time-resolved, steady-state, and modulated measurements. It covers methods for handling tissue optical properties and boundary conditions, with applications in spectroscopy and imaging.

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Area of Science:

  • Biomedical Optics
  • Computational Physics

Background:

  • Understanding light propagation in biological tissues is crucial for developing advanced medical imaging and spectroscopy techniques.
  • Accurate modeling of light transport is essential for interpreting experimental data and designing new optical diagnostic tools.

Purpose of the Study:

  • To provide a tutorial introduction to the fundamental principles and computational methods of diffuse light transport.
  • To outline analytical and numerical techniques for modeling light propagation in complex biological tissues.

Main Methods:

  • Introduction to basic analytic equations for time-resolved, steady-state, and modulated light transport.
  • Description of the perturbation method for optical property heterogeneities.
  • Explanation of boundary condition treatments, including air/tissue interfaces.
  • Presentation of finite mesh-based numerical methods for complex geometries.

Main Results:

  • The tutorial outlines the theoretical framework for diffuse light transport.
  • It details numerical methods for calculating light fields in heterogeneous tissues.
  • Applications demonstrate the utility of these tools in tissue spectroscopy and imaging.

Conclusions:

  • The presented theoretical and computational tools provide a foundation for analyzing light transport in biological tissues.
  • These methods are applicable to various applications in biomedical optics, including spectroscopy and imaging.